Scientists from the RCSI University found out how to stop excessive inflammation in the body. We are talking about the regulation of important leukocyte immune system, reported in the journal Nature Communications.
The immune system is capable of performing a double function - to help the body to recover faster after injuries, colds and lead to cardiopathology, negatively affecting coronary vessels. Immunity not only struggles with infections, but at the same time initiates inflammatory processes that cause the disease. When any pathogen is trying to harm the body, inside chemicals that cause the immune response required to combat the problem are distinguished. Excessive supply of immune signals with many bacterial infections may prevent recovery and worsen the patient's condition.
The study shows that protecting the body from damage provoked by inflammatory diseases is possible. According to the author, Claire McKoy, excessive inflammation is characteristic of most diseases, including arthritis, sclerosis, and inflammatory bowel disease. "Thanks to our discovery, you can develop new funds for the treatment of inflammatory diseases and, ultimately, improve the lives of people with these states," added to McKoy.
When macrophages, white blood tales in the body are exposed to infectious agents, a powerful inflammatory protein is produced, called cytokines, allowing to deal with invading infection. However, if the level of cytokines is out of control, significant tissue damage can occur.
According to the results of the study, protein, known as Arginas-2, limits inflammation, working through mitochondria - energy source for macrophage cells. This is important to reduce powerful inflammatory cytokine, called IL-1. Researchers said that the discovery could help develop new treatments aimed at Arginase-2 protein. This will help protect the organism from uncontrolled damage caused by inflammatory diseases.
Why do you need to treat chronic inflammation?
Chronic inflammation leads to a violation of the inflammatory response of the body and can cause damage to healthy cells and organs, which can lead to damage to DNA, the death of tissues and the internal scarring. All this is due to the development of chronic diseases, such as cancer, heart disease, type 2 diabetes, obesity, asthma, rheumatoid arthritis and neurodegenerative diseases, including Alzheimer's disease.Natural ways to combat inflammation
In order to cope with chronic inflammation in a natural way, foods with a high content of antioxidants and polyphenols should be eaten, such as olive oil, tomatoes, nuts, orates and fruits. Those who are trying to control inflammation, it is important to avoid refined carbohydrates, fried food, red and treated meat.