Abasebenzi belebhu ye-physics yezokwelapha eParis (ESPCI Paris-PSL, Inserm, CNRS) benze imephu i-Mepmer The Mevil Netture Network, kubikwe ocwaningweni olushicilelwe e-The Nature Biomedical Engineering Engineering. Lokhu kwenzeka ngenxa yendawo yokuzalwa kwe-ultrasonic yesimo se-Ultra-high sokulungiswa, kanye ne-sonography ephansi ye-ultra kanye nokusetshenziswa kwama-ejenti okuhlukana.
Imithambo yegazi ebuchosheni iyinethiwekhi eyinkimbinkimbi kakhulu enikeza ama-oxygen kanye nezakhi zomzimba. Kulandela kulokhu lowo msebenzi we-vascular ne-neuronal uxhumeke kakhulu, futhi ukuphazamiseka emikhunjini kubhekwa njengembangela enkulu yokuphazamiseka kwemizwa eminingi. Ukuxilongwa nokwelashwa kwalezi zifo kuyinkimbinkimbi ngokuntuleka kolwazi mayelana nemisebenzi yemithambo yegazi emincane nemikhawulo ekuboneni ngeso levarebescular.
I-aniography ehlanganisiwe ye-tomographic kanye ne-magnetic resonance angiography yizindlela ezimbili ezivame kakhulu zokuthola isithombe semithambo yegazi. Bamboza imithambo emikhulu efinyelela kububanzi ngamamitha ambalwa, kepha ayikwazi ukubona ama-capillaries amancane. Ngaphezu kwalokho, i-angiography ayinikezi imininingwane enamandla ngenethiwekhi yemithambo esikalini ehlukahlukene yendawo.
Isinqumo esiphakanyiswe ngababhali besifundo esisha kufanele sigcwalise igebe leli, ngoba linikeza izithombe ezinamandla zokusakazwa kwegazi kwalo lonke inethiwekhi yemithambo - kusuka kuma-arteraries amancane kuya kuma-capillaring amancane. Ngaphezu kwalokho, lobu buchwepheshe bungahlaseli, bungahlangene, bulula futhi ngeke budinge ukutshalwa kwezimali okubucayi.
Ithimba le-Mikael Tanterter lisebenzise i-sonography esheshayo ye-Ultra-Fast - isifundo esingahlaseli somzimba esisebenzisa amagagasi e-ultrasound, sivumela izinkulungwane zezithombe ngomzuzwana. Ngemuva kwalokho izinto ezihlukile zahamba zizohamba: Ngenxa yalokho, ama-micropulul aqhamuka ephepheni le-biocoompospeable, alawulwa ngaphakathi, asakazwa phezu kwawo wonke amathambo engqondo. Baboniswa ngezwi ngesimo se-ultrasound, sabekwa ekhanda lesiguli, ethempelini. Ngokuthola isikhundla sezigidi zama-microbubble amasekhondi ambalwa, ososayensi bakwazile ukubuyisela i-anatomy yenethiwekhi yemithambo kuze kufinyelele esikalini sama-micrometers angama-25, ngenkathi beqoqa imininingwane ngezakhi zendawo ezinamandla zokugeleza kwegazi.
Le ndlela yaqulwa ezilwaneni ezincane zelebhu ngo-2015, kepha ukwenza izithombe zobuchopho abadala aziphumeleli. Inkinga ukuthi, okokuqala, isiginali ye-ultrasonic ihlanekezelwe lapho idlula ekhanda, okuholela ekuwohlokeni kwekhwalithi yesithombe. Okwesibili, kwakudingeka ukuthuthukisa ama-algorithms alungiselelwe ukunyakaza, ngoba noma yikuphi ukunyakaza okuncane ebuchosheni kuvimbela amathuba okuba yi-microcubilization ngokunemba kwe-micron.
"Le" Premiere Premie "yezwe" kungenzeka ngenxa yokuqaliswa okuhlanganyelwe kwezindlela eziningana. Okokuqala ukubonwa kwe-Ultrafast, okunikeza inani elikhulu ledatha isikhathi esifushane kakhulu futhi kukuvumela ukuthi uhlukanise phakathi kwesiginesha ye-acoustic somuntu ngamunye we-microfubection. Lapho-ke ukwenziwa kwe-Ultrasound kwasusa umkhawulo wemvume lapho isithombe sento encane siyi-stain efiphele - ngaphezulu kwento yangempela. Kepha uma le nto ifakwe, ingaba nengqondo ukucabanga ukuthi indawo yayo ngqo isikhungo sebala elifiphele. Emacaleni ethu, ama-microbubble ajikeleza egazini adlala indima yezinto ezifakiwe futhi akuvumele ukubuyisela indawo ngqo yomkhumbi ngamunye wegazi. Ekugcineni, ukubhaliswa kwama-echo MicroBbubbles kuhlinzeke ngegagasi elivela entweni ehlukaniswe yi-micron, futhi, ngakho-ke, kwavunyelwa ukubuyisela okwenzeka ngesikhathi sokusatshalaliswa kwegagasi ukuyolungisa ukuphazamiseka okutholakalayo, "kusho uCharlie Demeniené, a Umbhali wokuhola wesifundo.
Ngenxa yentuthuko yayo, ososayensi sebevele bakwazi ukulungisa imininingwane emincane kakhulu yokugeleza kwegazi okuyisiyaluyalu endaweni ye-aneurysm ebekwe phakathi kobuchopho besinye seziguli. Amathuba amasha okuvota ngemikhumbi evula indlela yokuqonda okungcono nokuxilongwa kwezifo ze-cerebrovascular, njengokuhlangothi izifo, kanye nezifo ze-neurodegenerative.
Ngaphezu kwakho konke, kufanelekile ukuthi kuqaphele ukuthi ukwenza lokhu okwenziwe nge-ultrasonic kulula kakhulu ukusebenzisa odokotela uma kuqhathaniswa nezindlela ezikhona, kunenzuzo enkulu futhi inyumbazane engaphansi - inqubo ingeke yenziwa eduze kombhede wesiguli.
Umthombo: Isayensi Enqunu