Intsholongwane ye-antibiotic-enganyangekiyo, enje nge-GECEC ST131, inokuthi izuze amathumbu omntu ngaphandle kwezifo eziphazamisayo. Nangona kunjalo, bayakwazi ukosulela amanye amalungu. Ke, zinxulunyaniswa nosulelo lwetraknoloji, ingqondo, i-peritoneum, igazi kunye nezixhobo zangaphakathi, ezinje ngee-cathertionat, iityhubhu zesondlo kunye needrain zesondlo.
Abaphandi kwiKholeji yezoNyango yeBelora bachonge isicwangciso esitsha esisusa i-bacteria ngaphambi kokuba bangele usulelo. Indlela isebenzisa i-bacteriophas ezinokuthi zibekwe kufutshane nemicroorganisosm kwi-gestrointenal iphecana-Iqhuba uhlaselo kunye nentshabalalo elandelayo ye-bacteria. Iinkcukacha zomsebenzi zipapashwa kwiphepha leMagazini Mbio.
Iqela lafumanisa ukuba kukho imbangi kumathumbu ezilwanyana, ezithintela izigaba zokutshabalalisa iintsholongwane. Yachongwa njenge-mucins - iiproteni ezinamathela zenza umaleko phakathi kwe-epitisheltes yamathumbu kunye nomaleko wee-microorganisms.
Emva koko izazinzulu zijongile amanzi amdaka kunye neentsika zezilwanyana kwiibarteriwaphas ezinepropathi eyahlukileyo exhasa ukutshabalalisa i-bacteria phambi kweeguga. Ke bafumana iphageyi entsha ebizwa ngokuba yi-Es17: Ibopha ukuya kwi-mucuns kwaye ke inokutshabalalisa iintsholongwane kwindawo edibeneyo. Ezinye izifundo zibonakalise ukuba i-ES17 inxulunyaniswa neemolekyuli ezithile ezibizwa ngokuba yi-heparasulfate, enokufunyanwa kuphela kwii-mugs, kodwa nakumphezulu weendidi ezahlukeneyo zeseli, kubandakanya i-epitilial.
Oku kukhuthaza abaphandi ukufumana ukuba ukubopha kwe-wimilfate kunye neeseli ezichazayo ukunceda i-ES17 njongo kwaye kutshabalalise intsholongwane kwindalo esingqongileyo. Iingcali zebhayoloji zihlole impembelelo yephagesi ye-ES17 kumnini wayo weentsholongwane kwi-Internane kwi-Istine yeMouse kwaye ithelekiswa nempembelelo yeziqhinga ezingakwaziyo ukuzimela kwiimeko ezinzima.
"Sifumanise ukuba kuphela i-ES17 inobuchule obukhethekileyo bokujonga kunye nokuphelisa i-bacteria kwiimodeli zezilwanyana," utshilo uGqr Sabrina luhlaza, umbhali womsebenzi. Abaphandi bacebisa ukuba ii-bacteriophages ziyakwazi ukwenza oku ngaphambi kwe-microriganasms isulele amalungu.
"Sabona kwangaphambili ukuba ukujolisa kwindawo yokuma komhlaba kuya kuba yindlela yokusebenzisa iziyobisi ezibonakalayo kwixesha elizayo. Amalungiselelo awayi kuhanjiswa nje kuwo wonke umzimba ngethemba lokuba icandelo liza kuba kwindawo elungileyo. Ziya kuswa kuphela. Umsebenzi wethu kunye ne-fagami yimeko yokuqala xa le nto yenziwe "," Entoni Marso ishwankathelwe, umkhonzazana wesifundo.
Umthombo: Inzululwazi yezeSwaziya