I-American Vermex Amaricals (NASSDAQ: I-Vrtx) yenye yeenkampani ezinkulu ezikhula ngokukhawuleza. Ukunyuka okungafikeleli kwi-2025 - 10% ngonyaka. Inkampani isebenza kakuhle kuphuhliso kwicandelo lezifo zemfuza kwaye eneneni kuphela evelisa iziyobisi ukusuka kwi-fibrosis (isifo semfuza yamalungu amdaka). Inika ithuba elibalulekileyo lokhuphiswano, ukuhamba kwemali okuthembekileyo kwaye kuthetha iiprojekthi ezintsha.
Ngoku inkampani ikwazama ukwahluka komgca weziyobisi kwaye iya kwezinye iindlela ze-niche, umzekelo, i-anemia.
Ekupheleni kuka-2019, i-Arhente ye-American Federm yemveliso kunye nolawulo lweziyobisi zivumile ukudityaniswa kwamachiza kwi-fibrosis (trikafta / kaftrio). Amayeza amatsha kunokwenzeka ukuba abe ngumqhubi wokukhula okukhulu kwentengiso. Kufuneka ivumele ukutshintsha amalungiselelo amathathu amadala enkampani kwaye ngaloo nto ukwandisa isampuli evumelekileyo yezigulana ngaphezulu kwe-1/3 (ngenxa yeendlela ezibanzi).
Iziphumo zekota yesi-4 yama-2020 abatyali-mali abadakumbileyo, ngaphandle kwezalathisi ezichukumisayo. Ukukhula kwentengiso ehamba kunye nokukhula kweNzuzo, kodwa ukusilela kancinci kwee-EPs kukhokelele kwithontsi lemali ngenxa yekowuteshini ngenxa yolindelo oluphezulu. Oku kungaphindwa kwixesha elizayo.
Izitokhwe zibuze kwaye zadideka ingenelo ngaphezulu kwentengiso, ukusukela ngo-Okthobha kulo nyaka wonke inkampani yayeka ukuphuhlisa ichiza elivela kwintsika ye-alpha-1-antipripriprip. Nangona kunjalo, i-vertex iphuhlisa amayeza avela kwisifo esinye, idatha yeklinikhi ilindelwe kwisiqingatha sokuqala sika-2021, esinokukhokelela ekuguqukeni.
Xa kuthelekiswa nesampulu yeenkampani ezifanayo (i-biotechnology i-bindology), i-vertex iqulathe oovimba bemali ebonakalayo (kabini inqanaba lenkampani). I-roe vertex yi-37%, engaphezulu kwezihlandlo ezintlanu umyinge wesampulu. Ukusuka kwindawo yezalathiso eziqikelelweyo, kufanelekile ukuba ibalaselise i-P / FCF vertex ngokuchasene nesampulu (i-19 neli-29, ngokwahlukeneyo), nto leyo ethetha ithegi efanelekileyo yenkampani ukuba ivelise ukuhamba kwemali. Kwizalathiso eziqikelelweyo, inkampani irhweba kwindawo yemilinganiselo yesampuli.
I-Engnyy Shatov, Iqela Elilawulayo "I-BUSRELLE"
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