Satellite-V vaccine, developed in the Russian center of epidemiology and microbiology named after Academician N. F. Gamaley, was the second in popularity to the preparation for the prevention of COVID-19. According to the official twitter account, Satellite-V approved for use already in 45 countries.
In the first place - Vaccine from Astrazeneca and Oxford University (permitted in 49 countries). Surprisingly, after all, at first, this drug criticized for insufficient efficiency. On the third line (43 countries) there was a vaccine from the American Pfizer and the German startup Biontech, which was so praised in the West. Not included in the top 3 drugs from American Moderna, Chinese Sinopharm, Sinovac and Cansino. Close a list of one-component vector AD26, using a non-replicating genetically modified person's adenovirus, from Johnson & Johnson.
In addition to Russia, Satellite-V in recent months has received permission to Belarus, Argentina, Serbia, Bolivia, Algeria, Palestine, Venezuela, Paraguay, Turkmenistan, Hungary, UAE, Pakistan, Iran, Guinea, Tunisia, Armenia, Mexico, Nicaragua, Lebanon, Republic of Serbian, Myanmar, Bahrain, Montenegro, Saint Vincent and Grenadines, Kazakhstan, Uzbekistan, Gabon, San Marino, Ghana, Syria, Kyrgyzstan, Guyana, Egypt, Honduras, Guatemala, Vietnam, Moldova, Slovakia, Angola, Djibouti , Republic of Congo, Sri Lanka, Laos and Iraq.
A month ago, the results of the third phase of the test "satellite-V" appeared in the respected medical journal The Lancet. Efficiency amounted to 91.6% three weeks after the first dose, and in people over 60 years of age, this indicator was 91.8%. Since no one fell in a heavy form in the vaccine group (in the placebo group there were 20 cases), scientists concluded that the "satellite-V" protects 100% from severe COVID-19 forms. At any time after the first injection, and to the second estimated efficiency of the Russian vaccine was at the level of 73.1% - such results showed no other similar drug.
Among the other advantages of the "satellite-V" is that it was developed on the basis of two vectors of the recombinant adenovirus of different types, that is, a virus that "carved" genes responsible for the development of infection. The drug can be transported and stored in thermocontainers with dry ice, refrigerator bags and automatics. At first, the required transport temperature was set for minus 18 degrees Celsius and below, but then the Ministry of Health simplified the requirements: now the vaccine can be maintained at a plus two-eight degrees.
No serious reactions after vaccination "satellite-V" did not reveal, except for pain and redness at the place of injection, headache, increased fatigue, as well as symptoms resembling flu (for example, temperature). At the same time, some Pfizer and Moderna grafted in the test stages noted unpleasant side effects: not only banal headache and elevated temperature, but also unexpectedly - temporary paralysis of the person (Bella paralysis).
The other day, researchers from the Massachusetts Hospital of the General Profile announced skin reactions that manifest themselves some time after vaccination with MRNA-1273 from the American company Moderna. So, during the third stage of clinical trials of the drug, some grafts observed slower hypersensitivity of the skin (from four days to 11 days after the first dose, in the middle symptom manifested itself on the eighth day and disappeared in a week).
According to experts, the reason for extensive redness around the place of the injection, sometimes accompanied by itching and pain, it has not yet been possible to establish. Most likely, this is an allergic reaction.
Most patients were treated with ice and antihistamine preparations, although they needed corticosteroids, and antibiotics were mistakenly appointed. According to researchers, doctors should be prepared that such complaints will be received from the past vaccination. "Deferred skin hypersensitivity as clinicians and patients can be confused with skin infection," said Eric Shenya report co-author, doctor of medical sciences, departure of the hospital infectious control department. - These types of reactions, however, are not considered infectious, so they cannot be treated with antibiotics. "
Source: Naked Science