Ukulimala kwentambo yomgogodla okubangelwa yizingozi zezemidlalo noma zethrafikhi kuvame ukuholela ekukhubazekeni, njengokukhubazeka komzimba. Kubangela ukulimala kwezinqubo ezinde ze-cylindrical zamangqamuzana ezinzwa, okuthiwa anjns. Baphethe imininingwane evela ebuchosheni kuya emsipha nasemuva - kusuka esikhunjeni nasemisipha. Uma izinqubo zilinyazwe ngenxa yokulimala noma ukugula, lokhu kuxhumana kuyaphazamiseka.
I-AXANS ayikwazi ukukhula - kusho ukuthi iziguli zizohlushwa yizo zonke impilo. Kuze kube manje, azikho izinketho zokwelashwa ezingabuyisela imisebenzi elahlekile kuzisulu.
Uma ufuna ukwelashwa okungenzeka, iqembu elivela e-University of Ruhr lahlolwa yi-Hyper-Interleukin-6 Protein (Hil-6). "Lokhu kubizwa okuthiwa yi-Designer Cytokine. Akenzeki emvelweni, kukhiqizwa kusetshenziswa ubunjiniyela bezakhi zofuzo, "kuchazwa udokotela waseDitmar Fisher. Imininingwane yomsebenzi yanyatheliswa ejeni lezokuxhumana nge-Natural.
Phambilini iqembu elifundwayo libonise ukuthi ama-hil-6 angavuselela ngempumelelo ukuvuselelwa kwamangqamuzana ezinzwa ohlelweni lokubuka. Manje ososayensi baphoqa amaseli ezinzwa e-motor ne-cortex yezinzwa ukuze akhiqize ngokuzimela iprotheni ye-hyper-interleukin-6.
Kulokhu, basebenzise amagciwane alungele ukwelashwa kwezakhi zofuzo. Babejovwa ebuchosheni, futhi baletha uhlelo lokukhiqiza lwamaprotheni kumaseli athile ezinzwa - izimoto. Lawa maseli nawo ahlotshaniswa namagatsha aseceleni angezi-axonal ngama-neurons kwezinye izindawo zobuchopho, ezibalulekile kwinqubo yokuhamba, njengokuhamba. I-Hyper-Interleukin-6 nayo yahanjiswa kuleli cell bezinzwa - njengomthetho, kunzima ukutholakala - futhi kukhishwe lapho.
Ngakho-ke, ukwelashwa kwe-gene kwamangqamuzana ezinzwa eziningana kwavuselela ukuvuselelwa kwe-axenial kwama-neurons ahlukahlukene obuchopho namapheshana ezimoto ambalwa entanjeni yomgogodla ngasikhathi sinye. Ngenxa yalokhu, kwavumela amagundane aphephe ngaphambili lapho kwahlolwa khona ukwelashwa okuhlola, aqale ukuhamba ngamasonto amabili noma amathathu. "Kwaba isimangaliso esikhulu ngathi, ngoba ngaphambi kokuthi singaziboni izibonelo zokubuyisela izinto zemoto ngemuva kokukhubazeka okugcwele," kusetshenzwa umdobi.
Manje iqembu lokucwaninga libheka ukuthi kungenzeka yini ukuhlanganisa le ndlela nabanye ukuze basebenzise inqubo yokusebenzisa i-hyper-interleukin-6 kuya emzimbeni wezilwane ezincelisayo futhi uthuthukise umphumela. Baphinde bahlole ukuthi iprotheni "yomqambi" iyasebenza i-hyper-interleukin-6 kumagundane anokulimala okudala. "Kubaluleke kakhulu kubantu," kugcizelelwa i-Fisher. - Ukuhlolwa kwesikhathi esizayo kuzokhombisa uma kungenzeka ukudlulisela indlela kumuntu owakhelwe yithi. "
Umthombo: Isayensi Enqunu