Umsebenzi unyatheliswa embikweni wesayensi wesayensi. Ngo-2016, umagazini ogunyaziwe iLancet Neurology wethule imiphumela yocwaningo oluyitiye eliluhlaza oluwusizo kubantu nge-Down syndrome - kungathuthukisa isimo sabo sengqondo. Isibonelo, amandla okukhumbula amacebo athile wokuziphatha noma azivumelanise nesimo esithile. Kuyathakazelisa ukuthi ukuthuthukiswa okunjalo kwengqondo sekugcinwe ezinyangeni eziyisithupha ngemuva kokudlula inkambo eneminyaka yobudala yokuqeda i-Green Tea Extract. Lo mphumela uhlotshaniswa nento equkethwe itiye eluhlaza - i-Epigalealethin-3 Gabut.
Ukutadisha okusha kososayensi abavela emanyuvesi aseCentral Florida (USA) kanye ne-Barcelona, iSpain Institute of Science neTechnology (Spain) kanye nesikhungo sokwamukelwa kwe-molecular yezilwane ezincane (belgium) kuboniswe ukuthi kukhishwe itiye eliluhlaza futhi kuyakwazi ukuthonya ushintsho lwe-pathological kumuntu ezinganeni nge-Down syndrome. Kepha kungcono ukuthi ufake ekudleni kuphela ngaphansi kweminyaka emithathu - ngemuva kwalonyaka okukhishwe ngeke kulethe imiphumela elindelekile.
Ngasikhathi sinye, ukuqoqwa okukhulu kwe-epigallocatechin-3-gadut kungalimaza futhi, kunalokho, kuphazamise ukuthuthukiswa kwamathambo nobuso. Ingxenye yokuqala yocwaningo lwenziwa amagundane, owesibili - ezinganeni ezine-Down syndrome noma ngaphandle kokuxilongwa okufanayo. Emsebenzini "ekwelashweni" amagundane, itiye eliluhlaza laqala ngisho nangaphambi kokuzalwa komusha: imithamo ephezulu yetiye kwezengezwa kumanzi okuphuza, khona-ke ayengamagundane. Ngenxa yalokhu, amaphesenti angama-60 okuzalwa azalwe nge-Down syndrome ayenomumo ofanayo noma acishe acishe afanayo ngesihlakala esisemagukeni anempilo eqenjini lokulawula.
Ngokugxila okuphezulu kokukhishwa kwetiye eliluhlaza, imiphumela ibingafani kangako - kwezinye izimo ifomu lobuso, kunalokho, lahlanekezwa. Futhi hhayi nje kuphela ngabancane nge-Down Syndrome, kodwa futhi nasegunjini eliphilile. Ingxenye yesibili yocwaningo yayihanjelwa izingane ezingama-287 ezineminyaka engu-287 ezivela eminyakeni engu-18, kubandakanya abafana nge-Down syndrome futhi inempilo. Ngaphambi kokuqala umsebenzi wazo zonke izingane, zithathwe izithombe ngama-engeli ahlukene futhi walinganisa amapharamitha wawo.
Ngenxa yalolo cwaningo, kungenzeka ukuthi aqinisekise ukuthi iziguli ezinezingane ezathola imithamo eyanele yokukhishwa kwetiye eliluhlaza kusuka ku-zero kuya kweminyaka zishintshe izici zabo zobuso, ziye zifane nalezo ezifuywayo. Umphumela ofanayo, maye, awuzange ubonwe eqenjini lentsha. Lokhu kungenxa yokuthi kufakwe iminyaka emithathu izici eziphambili zobuso kanti nogebhezi lukhula ngokushesha okukhulu, bese ukukhula kwakhe kwehle.
Naphezu kwemiphumela ekhuthazayo, ososayensi banxusa ukuba bahlobane nabo ngokuqapha, ngoba kwenziwa kuphela ucwaningo lokuqala. Bagcizelela ukuthi kudingeka umsebenzi owengeziwe ukuhlola ithonya lokungezwa kwetiye eliluhlaza emzimbeni wezingane ezincane. Ngaphezu kwalokho, kuyadingeka ukuthola umthamo ofanele wezingane ukuze ungabingeli umphumela ohlukile.
Umthombo: Isayensi Enqunu