Izifo zenhliziyo ziyimbangela enkulu yokufa nokukhubazeka emhlabeni wonke. Kodwa-ke, iziguli zithambekele engcupheni eyandayo yokuthola izifo zenhliziyo kungazigwema, ngokuhamba kwesikhathi ngokushintsha indlela yokuphila nokuthatha imishanguzo efanelekile. Maye, ezimeni eziningi zezifo ezihlala zingabekezeleleki kuze kube yilapho infarder ye-myocardial yenzeka noma inhlangothi.
Ngakho-ke, kubalulekile ukunquma ama-biomarkers azosiza ukukhomba iziguli ngezifo ezifihliwe zenhliziyo. Abantu badalule kubo, njengoba wazi, uthambekele ekukhuphukeni kwemikhumbi (ukwephulwa kwendlela) ye-retina yeso - izicubu ze-multilayer zezinzwa ngenethiwekhi eyinkimbinkimbi ye-capillary. Ingaphezulu ne-Velcuses ejulile ye-Vascular ihlinzeka ngezingxenye zangaphakathi ze-oksijini naphakathi kwe-retina, ngenkathi ungqimba lwangaphandle luthola umoya-mpilo ku-choriocapillary. Nge-Occcusion Eqinile Yomkhumbi, izingqimba ezimbili zangaphakathi zalomhlaka lwezinzwa zingama-atrophy atrofically, futhi ngama-microfarct ama-microfar weso, njenge-maculopathy ye-paranteral aculopathy, ungqimba olujwayelekile luthintekile.
Usebenzisa ubuchwepheshe bokucabanga abangahlanyisiwe ngokulungiswa kwe-submillimeter ku-vivo kanye ne-tomography enambitha ngokuhambisana nayo, kungenzeka ukukhomba i-anomalies ezithombeni ze-retina okubonisa ukuthi i-ischemia: esigabeni esibuhlungu senuzi ungqimba lwe-mesh-shell. Izilonda ezinjalo zenzeka ngenxa ye-hypoperffusion noma i-microembolis efana nokukhuliswa kwe-artery nemithambo ye-retina, umfutho wegazi ophakeme, i-retinopathy ye-retinopathy ye-lickle cell anemia. Ukubonwa kwe-Microscience kukhombisa ama-voids wesiginali yokugeleza kwegazi esigabeni esibuhlungu, esiqinisekisa ukuthi imvelo ye-ischemic ifakwe ngenhla.
Abalobi bocwaningo olusha - Odokotela abavela e-University of California eSan Diego (USA) - bazama ukuthola ukuthi izilonda ezinjalo zamehlo zivame ukuwabikezela ngale ndlela. I-athikili ishicilelwe kumagazini i-EclinicalMedicine.
"Amehlo - iwindi empilweni yethu, izifo eziningi zingabonakala kubo. Futhi izifo zenhliziyo azifani, - ziphawulwe yiqembu lokucwaninga i-Mathieu Bachum, - Ischemia, okungukuthi, ukwehla kokugeleza kwegazi, okubangelwa yisifo segazi, kungaholela ekungeneni kwegazi esweni bese kuletha ukusatshiswa kwe amaseli we-retina, ashiya amathegi aqinile ". Sibabize ngokuthi yi-Ischemic Retivascular retina izilonda, noma ama-Ripled, futhi safuna ukuthola ukuthi bangasebenza yini njengezifo ze-biomarker zenhliziyo. "
I-Medics ifundele amarekhodi abantu abayi-13,940 abasedlule ukuskena kwe-OCT (i-tomography ehambisanayo) yendawo ephuzi - endaweni ephakeme kunazo zonke eCalifornia eSan Diego ngobufakazi obuhlukahlukene bemitholampilo kusukela ngoJulayi 1, 2014 kuya Julayi 1, 2019. Ngemuva kokuhlaziya i-Medkart, abacwaningi basakaze iziguli ngamaqembu amabili: Abantu abangama-84 banabantu abangama-84 ngezifo zenhliziyo ezibhaliwe, ngo-76 benempilo (ophulukayo, ukwehluleka kwenhliziyo, isifo sikashukela, isifo sikashukela Zombili lezi zinhlobo, isifo esivimba esingamavasi samaphaphu noma i-pulmonary hypetertension). Ngaphezu kwalokho, akekho noyedwa ababambiqhaza aveze izindlela ezihambisana naleso.
B) Ukuskena kwe-SD-Oct B, okubonisa ukuthi i-Ripling (Redxangle). I-NoticeAlbly Foccelful ABLARTION INL (umcibisholo obomvu), ehambisana nokunxephezelwa okuphezulu kwengqimba yenuzi emnyama (umugqa ophuzi). Kusuka)
Ukuvela kobuso obuyiselwe kusuka ku-scan enobuningi obukhulu obuhlangene kusuka ekuskeneni okulandelanayo kwe-B. Ukubukeka okuthathu okubukeka njengamachashazi amnyama (imicibisholo ebomvu) / © eclinicalmedicine
Kuyaziwa ukuthi ubungozi bezifo zenhliziyo e-United States bunqunywa kusetshenziswa umshini wokubala okhethekile we-ascvd owakhiwe yi-American College of Cardiologists. Ababhali bocwaningo bathola ukuxhumeka phakathi kwenani lezilonda ze-retinal leses (Riplip) kanye nokuhlolwa kobungozi kubalwa yi-ASCVD yawo wonke amavolontiya.
"Ezigulini ezinezikhombi eziphansi nezomngcele ascvd kwaba nenani elincane le-Righting emehlweni, kodwa njengoba ingozi i-ascvd yanda, inani le-rids lakhula. I-REST REGBIGL ngesiguli ngasinye yayiphakeme kakhulu eqenjini ngezifo zenhliziyo uma iqhathaniswa neqembu elilawulayo (2.8 ngokumelene no-0.8). Inani le-Righter likubantu abane-IBS nokushaywa unhlangothi kwakungu-2.4 no-3.7. Ezigulini ezine-infarction ye-myocardial, inkomba ye-rup yaphenduka engu-3-4 - iqhathaniswa ne-1,3 Riplid ezigulini ezinama-IHS ngaphandle kokuhlaselwa yinhliziyo. Siphawule iningi lezilonda ezibuyiselwe ezigulini eziba nohlangothi. Njengoba i-retina ingukuqhubeka okuqondile kobuchopho, kungenzeka ukuthi ama-Riplist akhuluma ngesifo se-cerebral kunesifo se-coronary imikhumbi, "kusetshenzwa abaphenyi.
Ngakho-ke, imiphumela ikuqinisekisile ukuthi umonakalo we-retina - ama-biomarkers e-ischemic infecy infhemic yale ncwajana yangaphakathi yamehlo ajwayelekile ezigulini ezinezifo zenhliziyo futhi angasebenza njengesici esingeziwe sokubikezela kwabo nokutholwa. Ngokusho kwababhali bomsebenzi, uma odokotela be-ophthalmologist bethola isiguli esiphindayo, khona-ke kufanele ithunyelwe ekwamukelweni nakwisifo senhliziyo.
Umthombo: Isayensi Enqunu