Ososayensi baseRussia njengamanje bakha indlela yokuhlonza nokuhlola eVitro (ku-tube) ye-bioactivity yezidakamizwa ezilwa nokuvuvukala zisebenzisa amaseli ezinto eziphilayo. Lolu cwaningo lwenziwa ngohlaka lwencwadi yombuso yoMnyango Wezempilo weRussia Federation.
Njengoba ochwepheshe abamele iSamara Medical University, indlela entsha izosiza ukuhlola ukusebenza kahle okujwayelekile uma kuqhathaniswa nezidakamizwa zangempela, kanye nokuthola imishwana (inkohliso) yemithi. Njengengxenye yocwaningo kumaseli, izidakamizwa ziyahlolwa, ezinomsebenzi wokulwa nokuvuvukala futhi zihlose ukwelashwa kwezifo ezinjengesifo se-crohn, i-rheumatoid arthritis, i-psoriasis, njll. Ngenxa yalokho, ukusebenza kwangempela komuthi omusha kunqunywe. Kulokhu, amasistimu wokuhlola athuthukiswe kuwo wonke amanani amaseli abantu akhiqiza inqubo yokuvuvukala ukuvuvukala kwento - ama-cytokines. Ukusebenzisa umbono onjalo, amaseli "atshalwe" emithonjeni yasekuqaleni lapho akhula khona ngaphansi kwemibandela ye-adle izakhi. Lapho usuqede umjikelezo wokukhula, amaseli avuselelwa ukukhiqizwa kwama-cytokines, ngemuva kwalokho, ukusebenzisa imithi, le nqubo icindezelwe. Isigaba sokugcina singukuhlola nge-IFA kutholakala ukusebenza kahle kokuqaliswa kokusebenza okungenhla. Ukuqashelwa kwesidakamizwa sezokwelapha kuyasebenza uma kwenzeka kunqanyulwa ngaphansi kwesenzo sawo sama-cytokines.
Kuyaphawuleka ukuthi umsebenzi wesayensi usuvele uqhubeka iminyaka emithathu, futhi hhayi kudala, isifundo sathola uxhaso lokwenziwa kwesabelo soMbuso kusuka koMnyango Wezempilo yaseRussia. "Umsebenzi wethu iminyaka ezayo ukufunda ukusebenzisa lezi zinhlelo zokuhlola ukuze ungaphandle komzimba u-Ex Vivo, kushubhu lokuhlola ukuthola imishanguzo ezosondela esigulini esithile. Kunezidakamizwa eziningi zokulwa nokuvuvukala, ngakho-ke kunjalo Kubalulekile ukunquma ukuthi yimuphi wabo ofanelekela isiguli esisodwa noma esinye ayengathathi yonke into elandelana. Lona okubizwa ngokuthi umuthi oqondene nomuntu uqobo, uProfesa uLarisa I-VOOVOVA.