Iqela lamazwe aphesheya laseMelika kunye ne-Chinebioological I-Microbiologicals iqhube kwisifundo apho wafunda amachaphaza e-Britan yoxinzelelo lwe-Britavirus. Kwavela ukuba utyekelo lwenguqulelo yoqobo yenza ukuba ikwazi ukunxibelelana nomzimba womntu kangangezihlandlo ezili-10 ngcono.
Kwinkqubo yophando, izazinzulu ezimele iYunivesithi yaseColorado (i-USA), kunye noogxa babo baseTshayina balungisa inani elikhulu leeproteri zaseBritane, ukuzama ukulinganisa i-receppes2, ngokuhambelana nokulinganisa. Iziphumo zovavanyo zithelekiswa neziphumo zemilinganiselo enjalo eveliswe ngomnye ubunzima be-coronavirus, engenalo i-N501y yophawu lwe-N501y luhlobo lweBritane. Njengoko yayihamba, into yotshintsho lwenqaku elincinci kwi-RBD ye-RBD yeproteni, enoxanduva lwecandelo le-SARS-2 ngomphezulu weseli, iphucule kakhulu amandla e-pathogen yokuqulunqwa kwe-repptors2. Kuyaphawuleka ukuba ngokomndilili, esi salathisi sidlula amaxesha alishumi, nto leyo, ngokweengcali, ifana ncamango phakathi kwe-coronavirus yohlobo olutsha kunye ne-SARS-cov, enomdla kwi-itpiconia enomdla.
Igqabaza ngeziphumo zokubala, ogqirha batsho ukuba utshintsho olwalubonakaliswayo ekusebenzeni kweeproteni ze-RBD lubangelwa kukuguqula inani lezinto ezihamba kunye ne-ACE2. Ukongeza, oochwephesha be-microbiologi bafumanise utshintsho olungakumbi oluchaphazela i-molecus molecule, kodwa indima yale metamorphosis kufuneka ifunyanwe. Kodwa sele kunjalo, izazinzulu ziqaphele ukuba utshintsho olukhankanyiweyo luyakwazi ukunciphisa ukusebenza kwesenzo esibonelelwa ngee-antibodies ze-britan. Nangona kunjalo, ngokweengcali, amandla okuchasa intsholongwane ngokuchasene nentsholongwane ngokuchasene ne-Covid-19 amayeza okuvumela intsholongwane ebaluleke kakhulu, nangona engeyonto ingako kwi-SARS-2.
"I-British Coronavirsus inezinto eziguqulweyo zenqaku kwi-N501y, itshintsha isakhiwo se-RBD protein, esinoxanduva lokususa intsholongwane kwi-ASA2 I-Readproptors iphucule ubuchule bentsholongwane ukuya Nxibelelana nale proteni yeeseli zabantu, "umbhali ophambili womsebenzi wesayensi, uNjingalwazi uPhilip Marrah. Izifundo zithunyelwa kumthombo we-Bhariorgiv ye-Intanethi.