Valeval Antibothy, e khonang ho sireletsa motho ho vaerase ea SV-Cov, boholo ba "beng ka bona" ​​le liphetoho tsa bona tse ka bang teng

Valeval Antibothy, e khonang ho sireletsa motho ho vaerase ea SV-Cov, boholo ba "beng ka bona" ​​le liphetoho tsa bona tse ka bang teng

Ho tšepisa Antibody Antibody Adg-2 e bile le sehlopha sa litsebi tsa Litsi tsa Patlisiso e tsoang ho Mekhatlo e Meholo ea US, mekhatlo e sa lefelloeng ke phaello le lifeisi tse peli tsa phaello. Liphetho tsa bo-ramahlale ba tsona ba mosebetsi ba hatisitse sehlopheng se hlahlobiloeng

Ho sa tsotellehe seo a se finyeletseng e tsotehang ha a bōpa ente eaba ba etsa maloetseng ho Coronavirus SARS-COV-2, COVID-19 causative moemeli, bona nako e telele katleho e ntse e belaetsang. Ha ho hongata ka lebaka la bofokoli ba lithethefatsi ka bo bona, joalo ka bokhoni ba vaerase haholo. Ho feta moo, boholo ba se seng se amohetse le liteko tse fetang tsa ente li sebelisoa e le sepheo sa karolo e tšoanang ea kotoho.

Antibod Antibod Antibod antibod antibody a ikarabellang bakeng sa ho kenya seleng e lebisitsoeng ke domain capude ea var-cov. Microfotography e entsoeng ke karolo ea cryweopy / © ea ka e pharalletseng khahlanong le li-vaerase tse matla joalo ka li-encorevady tsa Sars-Et al., Saense:

Re ntse re bua ka meaho e khethehileng re ikarabella Capsid ea Viral, e leng boikarabello ba ho kopanya seleng e tšoaelitsoeng - RBD). Libaka tsena li tlas'a liphetoho tse ngata 'me li ka fapana haholo lipakeng tsa mefuta ea vas ea vaerase e le' ngoe, eseng ho bolela mefuta e amanang. Ka hona, bafuputsi ba amerika ba ile ba tsepamisa maikutlo a bona mabapi le ho bula li-antibodies tse kanna tsa fetoha.

Baetsi ba joalo ba bitsoa li-antibodies tse kholo tsa li-antibodies, li sa nyenyefatse, li-bnabs) ebile li ka ba le motheo oa ho sireletsa batho bohle ba livaerase. Le ka liteko tsa nako e telele, ho ne ho ka khoneha ho etsa bonkgetheng 'maloa: ADG-1, ADG-2 le ADG-3. Ka lebaka la khetho, khokahano le khoutu ea ADG-2 e ne e sebetsa ka ho fetisisa.

Model Adg-2 e leng sebopeho se pharaletseng le se pharalletseng le livaerase tse matla tse kang sam., Saense 2521, doi: .1126 / saense.112330

Bokhoni ba eona ba ho hlasela Coronavire ha li hlahlojoe moetlo oa lisele tsa mouse, 'me lia khahla. ADG-2 e hokahana hantle le mefuta e fetang e meraro ea li-Sap-e nang le li-speed tse mpe haholo. Bo-rasaense ba bone setopo e tšepisang ho litlolo tsa mefuta e fapaneng, eo rbd e fapaneng haholo. Ke eng e khahlang haholo, ADG-2 e bontšitse bokhoni bo phahameng ba ho hokahanya "letsopa la boka-taba ea ba 19 Fuvid-19 - Sarbecovirus Subfavirus Subfadis Subfamitl.

Mohloli: Saense e hlobotseng