Data nyowani yesainzi TSu ichabatsira mukuongorora varwere vane stroke

Data nyowani yesainzi TSu ichabatsira mukuongorora varwere vane stroke

Mhedzisiro yekutsvaga inobudiswa mune yakakwirira-tech Journal International Jernal yeMolecular sainzi. Chinangwa chekudzidza chakaitwa neveurobiologists nerutsigiro rweRNF yaive yekufunda maitiro ekuumbwa kwetsva neurons neIschomic stroke. Kuti uite izvi, nzira itsva yekucherekedza madiki neuron yakasikwa.

Tsu masayendisiti pamwe chete nevanoshanda navo kuLivevene (Belgium) akagadzira "muchinjanisi" kutakura zvinhu zvemberi mumasero ehuropi - anokosha maviru uye maAdensass vasova. Nzira yakafanana yekuendesa genetic zvinhu ikozvino yashandiswa paunenge uchigadzira mamwe maccins uye zvinodhaka.

Majinjini genetic akaiswa muhutachiona husina kurerana kwetirlitin protin gene uye yakanyanya kukosha genetic iyo inokubvumira kuti uwedzere kugadzirwa kwemukati chete mumatambudziko emakore. Mwana mudiki akaunganidza ferritin ane maatomu esimbi anogona "kuona" kana uchishandisa chaiyo mri protocol.

Kucheka kwehuropi, kupendwa neantibodies kune protein ferritine (tsvuku) uye mucherechedzo weCD68 Macrophages (Green), uye MRI Mufananidzo wehuropi hwemhuka imwe chete. Miseve yakanyorwa nzvimbo dzemasumbu emasero akaunganidzwa ferrine, uye macrophages / © mufananidzo kubva kuChidziviriro yerabhoritari yeNaurobiology Tsu

"Patinoratidzira uropi hwemhuka, hwakaona nzvimbo mbiri neshanduko chaiyo muMRI chiratidzo cheCerritin, anodaro musoro weiyo neurobiology labhoritari yeBB TSU Marina Khodanovich . - Chikwangwani chakanyorwa munzvimbo isiri-yehemic, kupi, mushure mekurohwa, iko kusinga danho remumushe neuron kazhinji kunowanzova kutanga. Izvi hazvina kushamisika kwatiri, asi kuvapo kwechiratidzo chimwe chete muchirongwa chekurohwa kwakazoitika kuti tisatarisirwa. "

Chidzidzo chinotevera chezvikamu zvehuropi zvakaratidza kuti chiratidzo chakadai chakapihwa macrophages - izvo zvichiri kunzi "vanodya" kubva kune rimwe giredhi. Μαόόό - - - hombe, uye bigάάο - Macrophages anokwanisa kubatwa neanoshanda uye kugaya butteria, mutorwa kana muchetura kana zvidimbu zvidimbu zvemasero akafa. Pashure pehuropi sitiroko, MacPhawses anotama kuIschemic anotarisisa, uko chete mitezo yemutyairi chete yakabviswa, asi zvakare masero matsvuku eropa ari musimbi, nokudaro achionekwa "paMRI.

Masero avakaunganidza simbi uye ferrine yakabviswa nehuremu hukuru. Mutsetse wepamusoro - immunohistochemical staining for ferritin (Ferrh), Neuron mamakisi (neun) neMacrophagy (CD68). Yakadzika Range - Runyorwa rweHwunhi Pendi nePerls pane ISSE ZVESANGANO mumasero / © photos

Maererano neurobiologists, TSU, TSU, kucherechedzwa kwemasumbu eMacrophages kushandisa MRI kunogona kushandiswa kugadzira nzira itsva yekuongorora, iyo ichabatsira vanachiremba vanachiremba. Iyo tekinoroji ichabvumira kuongorora kukura kwekuzvimba mukusavimbika kwekurwiswa, kuti uwane rumwe ruzivo nezve mamiriro emurwere, zvakanyanya kufanotaura kosi yechirwere uye kusarudza kurapwa kwezvinodhaka.

Iye zvino basa guru raunoda kugadzirisa neurosciologists kuwana nzira yekusiyanisa masaini kubva kuMacrophages uye mutsva neuroni neine genetic labels. Kune izvi, zvakafanira kuenderera mberi nekumwe kuongorora kuitira kuti uwane ruzivo rwehunhu hutsva nezvehunhu hweMacrophages uye mutsva neuroni mukutarisa kweiyo ischemic kukundwa kwe ischemic yekukunda ischemic. Panyaya yekunyadzisa rnf rnf, chirongwa chitsva cheTsu masayendisiti anozotarisirwa kugadzirisa aya mabasa.

Kunobva: Naked Science