Iyo yekuvimbisa antibody adg-2 yakagadzira boka revanyowani kubva kune akati wandei US masangano, asiri-purofiti masangano uye maviri mafomu ebhiri. Mhedzisiro yavo masayendisiti ebasa vakaburitsa muJurnal Science American Association yekuvandudzwa kwesainzi (aaas).
Pasinei nezvinogona kufadza pakugadzira maccines achiumba kudzivirirwa kuCoronavirus vanochengetedza-cov-2, kuwanda-19 Kwete zvakanyanya nekuda kwekukanganisa kwemishonga iyo pachavo, zvakanyanya sekugona kwemavhairasi nekukurumidza. Uyezve, ruzhinji rwekare rwakatenderwa uye rwakatotenderwa nePlcine bvunzo dzinoshandiswa sechinangwa chechikamu chimwe chete chehurumende.
Tiri kutaura nezvematanho akakosha paganda reiyo hutachiona hwehutachiona, izvo zvine mutoro wekusanganisa kune iyo yakatapukirwa sero - Receptor Binding Domain (RBD). Nzvimbo idzi dzinozviisa pasi pekuzvishandura uye dzinogona kusiyana zvakanyanya pakati pematambudziko ehutachiona mumwe, kwete kutaura zvakabatana. Naizvozvo, vaongorori veAmerica vakatarisa zvavakaita pakugadzira maantibodies izvo zvingave zvakanyanya.
Vamiririri vakadaro vanonzi vakaparadzirwa mapepa ekutora antibodies (zvakanyanya kusarerekera antibodies, Bnabs) uye inogona kuve hwaro hwekudzivirira kwemasendimita anokwanisa kudzivirira pakarepo kubva kune imwe mhuri yehutachiona dzese. Uye nekuedza kwenguva refu, zvaive zvinokwanisika kugadzira vanoverengeka vanokwikwidza: adg-1, adg-2 uye adg-3. Nekuda kwekusarudzwa, kubatana neADG-2 kodhi ndiyo yaive inoshanda zvakanyanya.
Kugona kwayo kurwisa kuCoronavirus kwakaongororwa mutsika yemasero emameve, uye zvinoshamisa. ADG-2 zvinobudirira zvinobatanidza kune anopfuura madhiri matatu gumi nemaviri ezvipfuyo zvisina kufanira-pasi-cov-2, ivava zvino kutyisidzira vanhu. Masayendisiti akasangana nemuviri unovimbisa pamatambudziko akasiyana-siyana, umo Rbd yakasiyana zvakanyanya. Chii chinonyanya kufadza, adg-2 yakaratidza kugona kwakanyanya kubatanidza "hama" dzakasiyana-siyana dzemakororo eCavid-19 - Sarbecovus vhiri.
Kunobva: Naked Science