Abahanga mu kigo cy'ubushakashatsi bw'ikigo nderabuzima cyabana muri Utah (Cri) bize igice cy'ibisimba + by'ingirabuzimafatizo (Lepr +), bitanga Osteolektin. Abahanga mu binyabuzima basanze selile zizengurutse imiyoboro y'amaraso y'amaraso mu magufa no kubungabunga lymphoide iri hafi. Ubushakashatsi bwabereye ku mbeba ya laboratoire. Ibisobanuro birasohoka mu kinyamakuru Kamere.
Nanone, itsinda ryashoboye kumenya ko selile nziza-nziza ikora icyicaro kihariye cya Cyistato na lymphoide zabanjirije ibyuma bikikije Arteriole. Ariko, umubare wingirabuzimafatizo ugabanuka hamwe n'imyaka.
Kugenzura niba inzira ishobora gupfunyika, bashyira ibiziga byambukiranya igihugu mu tugari twa laboratoire - kandi inyamaswa zashoboye guhugura. Byaragaragaye, kubera umutwaro uhoraho w'amagufwa, bakomejwe, mu gihe umubare wa Osteolektin-selile nziza na lymphoide abanjirije hafi ya Arteriol yiyongereye. Nicyo kimenyetso cya mbere gitera imbaraga imashini igenga niche muri marrow.
Byongeye kandi, abahanga basanze selile nziza ya Osteolektin-nziza yerekana reseptor ya Piezo1, ibimenyetso imbere mu Kagari zisubiza imbaraga za mashini. Iyo yakuweho, inyamaswa zacitse intege amagufwa n'abidadadahuhanga.
Rero, itsinda ryasanze imbaraga zaremwe iyo zigenda cyangwa zikora zanduzwa nubwato bwamaraso yamaraso mu magufa. Ibi bikangura selile ya Tiraharing na lymphocyabwobyimba no kugira uruhare mu gushimangira amagufwa nubudatubudadadaduco. Muri icyo gihe, niba badakora ubushobozi bw'akagari kamagufwa kugira ngo basubize igitutu cyatewe n'imitwe ya mashini, amagufwa azacika intege, kandi ubushobozi bwo kurwanya indwara bizagabanuka.
Hamwe na hamwe, aya makuru asobanura uburyo bushya bwo gushimangira amagufwa hamwe nimikorere yumubiri nimikorere yumubiri. Ati: "Ubushakashatsi bwashize bwerekanye ko amahugurwa ashobora guteza imbere imbaraga z'amagufwa n'ubudahangarwa. Umuyobozi wa CRI, Sean Morrison, Sean Morrison, umuyobozi wa CRI, twashoboye kandi kubona Mechanism, tubikesheje ibi bibaho, "Morrison wo mu kigo cy'ubuvuzi Howard Hughes.
Inkomoko: Ubumenyi bwambaye ubusa