Abahagarariye ubumenyi bugezweho bukora ubushakashatsi bwinshi kandi bwinshi bugamije uburyo bwo guhinga biva muri selile zabantu. Akenshi, ubushakashatsi nk'ubwo bukorwa ku nyamaswa zigeragezwa zibona ikiremwamuntu. Byaje kumenyekana ko abahanga bashoboye kwidagadura amarira y'umuntu ukomoka mu kagari ka Stem, muhindure imbeba zibigeragezo.
Imwe mumirimo nyamukuru ya glande yumuntu nubushobozi bwo gusiga amaso, kubarinda gutuma. Mu bwoko bumwebumwe bwindwara, glande za lacrase zireka gukora neza, zishobora kwangiza amaso. Ibi birashobora kugaragara muri syndrome yumye na Shegren, ariko kandi yangije izindi ndwara nyinshi kubushake bwamarira, nuko abahanga mu bya siyansi bashakisha uburyo bwiza bwo kugarura glande ya marira akoresheje guhinga no guhindura abarwayi.
Dr. Rachel Kalmann, umuganga w'amaso wo mu kigo nderabuzima cya kaminuza (Umc) muri Utrecht mu Buholandi yari umwe mu banditsi b'ubushakashatsi bushya. Ingingo ifite ibyavuye mu mirimo ya siyansi yasohotse mu gitabo cya Kagari. Dr. Kalmann nk'itangazo ku ntsinzi ye yatsinze ibi bikurikira:
Urugero "Dysfaction ya Glande ya Lacrimal, nk'urugero, muri Syndrome ya Shegon, irashobora kugira ingaruka zikomeye, zirimo gukama ijisho cyangwa ibisebe bya Cornea. Mu bihe bikomeye, ibi birashobora gutuma ubuhumyi. "
Ku cyiciro cya mbere, itsinda ry'abahanga riyobowe na Dr. Kalmann ryafashe ingero ya marike ya marira mu mbeba, gutora ibisabwa kugirango bidashoboka kubisubiramo muri laboratoire. Ku cyiciro cya kabiri, impuguke zakoze ubushakashatsi hamwe ningero za selile zabantu, mubyukuri zikura urugingo rusanzwe rwingirabuzimafatizo za microscopique.
Ku cyiciro cya nyuma, amarira ya marira yumuntu watewe imbeba yubushakashatsi igeragezwa mugukosora intsinzi. Abahanga mu cyiciro cyambere bakavuga kumwanya wo gutangira imbaga ya marira ya marira abantu baracyari kare, ariko nyuma yimyaka mike, ubwo buvuzi burashobora kubonwa nkimiti igezweho.