Acetate - Ethanol Metabolite, ikorwa na Alzyme. Irakora hamwe na aside ya mamma-amine (gamc) - feri NeuroUrumestator Sisitemu yo Hagati. Afite inshingano zukuntu umuntu wasinze yitwara. Kurugero, abantu borora inzoga bareba aldiciency. Ntibashobora rero kubyara vuba.
Mbere byakemejwe ko Ethanol Metabolism ibaho mu mwijima, kandi hamaze kuba byangirika mu bwonko. Icyakora, itsinda ry'abanyamerika ba Neurobologiste y'Abanyamerika bo mu kigo kugira ngo ubunebwe ibigo by'igihugu by'abantu ubuzima bwa Amerika bwasanze imbogamizi ya acetate ishobora kubaho mu bwonko. Byaragaragaye, bigaragarira muri cemisellum astrocytes kandi bigatera igihombo. Ibisobanuro birambuye byasohotse mu kinyamakuru Kamere Metabolism.
Abahanga mu bya siyansi bakoze iperereza ku mvugo ya MRNA Ahalh2 mu turere dutandukanye two mu bwonko ku bice 11 by'imbeba no mu bice bitatu by'ubwonko bw'umuntu. Byaragaragaye ko imvugo cyane igaragarira muri cerebellum, kandi nkeya murwego rwabanjirije.
Nanone, itsinda ryakoze ubushakashatsi ku mbeba. Kubwibyo, abahanga bazanye imbeba, mu bwonko bwatari Enzyme ya Alzyme. Noneho, ninyamaswa zisanzwe zahawe amafaranga make ya Ethanol (garame imwe kuri kilo yuburemere). Mugihe c'isesengura, byagaragaye ko inzoga zitera isura ya acetate muri orebellum. Ariko, imbeba zakomotse zagaragaye ko zirwanya ingaruka zinzoga, kubera ko Enzyme atagira inzoga atcetate, yakusanyije mubwonko. Mu mbeba nta allecytic Aldh2, hari kandi urwego rwo hasi rwa Gamke nyuma yo kunywa inzoga. Bityo guhuza neza.
Mu mboro hamwe no kubura enzyme mu mwijima, kwishingikiriza. Ibi byatumye abanditsi b'ubushakashatsi bafata ko isoko ya acetate muri sinobellum - inzoga, ntabwo ari Aldehyde. Ariko biracyagomba kwerekana.
Hanyuma, abahanga baza ku mwanzuro w'uko Alhh2 ENTNEMme, iherereye mu mwijima n'ubwonko, bigira ingaruka ku mubiri muburyo butandukanye. Bashaka gukomeza kwiga iyi enzyme mubantu. Nanone, abahanga bita astrocitindary alld2 intego ikomeye yo kuvura inzoga nyinshi nindwara zuzuye.
Inkomoko: Ubumenyi bwambaye ubusa