Asayansi ochokera ku yunivesite ya RCSI adazindikira momwe mungayimirire kutupa kwambiri m'thupi. Tikulankhula za malamulo ofunikira a leukocyte chitetezo, adanenedwa mu magazini yolumikizana.
Thupi la mthupi limatha kugwira ntchito kawiri - kuthandiza thupi kuti lizithanso pambuyo povulala, chimfine ndikutsogolera pa Carioopathogy, molakwika molakwika. Katemera osati zovuta zomwe zimangokhala ndi matenda, koma nthawi yomweyo zimayambitsa njira zotupa zomwe zimayambitsa matendawa. Pamene mankhwala aliwonse akuyesera kuvulaza thupi, mkati mwa mankhwala omwe amachititsa kuti chitetezo cha mthupi chisathe kuthana ndi vutoli. Kuchuluka kwa chitetezo chathupi ndi matenda ambiri amaboti amatha kupewa kuchira ndikuima.
Phunziroli likuwonetsa kuti kuteteza thupi kuwonongeka lomwe limawonongeka ndi matenda otupa ndi otheka. Malinga ndi wolemba, Claire Mckuy, kutupa kwambiri kwa matenda ambiri, kuphatikizapo nyamakazi, sclerosis, ndi matumbo otupa am'mimba. "Chifukwa cha zomwe tapezazo, mutha kukulitsa ndalama zatsopano zochizira matenda otupa ndipo pamapeto pake, pamapeto pake, kusintha miyoyo ya anthu omwe ali ndi mayiko awa," anawonjezera kwa McCoy.
Macrophages, mafayilo oyera mthupi amawonekera kwa othandizira, mapuloteni amphamvu otupa amapangidwa, otchedwa cytokines, kulola kuthana ndi matenda opatsirana. Komabe, ngati mulingo wa ma cytokines satha kuwongolera, kuwonongeka kwa minofu yayikulu kumatha kuchitika.
Malinga ndi zotsatira za phunziroli, mapuloteni, omwe amadziwika kuti Arlikas-2, amachepetsa kutupa, kugwira ntchito ku Mitokondria - mphamvu ya mphamvu ya macrophagege. Izi ndizofunikira kuchepetsa cytokine yamphamvu, yotchedwa Il-1. Ofufuzawo adati zomwe zapezazo zitha kuthandiza kukulitsa chithandizo chatsopano chomwe chimayang'anizana ndi mapuloteni a 1. Izi zithandiza kuteteza chiwalo chochokera kuwonongeka kosalamulirika chifukwa cha zotupa.
Chifukwa chiyani muyenera kuchitira matenda otupa?
Kutupa kwambiri kumabweretsa kuphwanya mawu otupa a thupi ndipo kumatha kuwononga maselo abwino ndi ziwalo zathanzi, zomwe zimatha kuwonongeka ku DNA, kufa kwa minyewa komanso kuchepera mkati. Zonsezi zimachitika chifukwa cha matenda osachiritsika, monga khansa, matenda a mtima, mtundu wa matenda a shuga, mphuno, matenda a asheumatiod, kuphatikiza matenda a Alzheimer.Njira Zachilengedwe Zolimbana ndi Kutukula
Pofuna kuthana ndi kutupa kwakukulu mwachilengedwe, zakudya zokhala ndi mantioxidants ndi ma polyphenols ziyenera kudyedwa, monga mafuta a maolivi, tomato, mtedza, zipatso. Iwo amene akuyesera kuwongolera kutupa, ndikofunikira kupewa zakudya zowoneka bwino, chakudya chokazinga, nyama yofiira komanso yokhazikika.