Pab neeg cov kws tshawb fawb thoob ntiaj teb thiab cov kws tshawb fawb cov microbiological ua ib qho kev kawm lub sijhawm uas nws tau kawm txog kev kis ntawm cov Coronavirus. Nws muab tawm tias qhov nyiam rau cov kev sib hloov qub ua rau nws muaj peev xwm sib txuas lus nrog tib neeg lub cev 10 zaug zoo dua.
Hauv cov txheej txheem tshawb fawb, cov kws tshawb fawb sawv cev rau lub tsev kawm ntawv qib siab ntawm British), sim ua kom muaj cov asreate receptors2, hauv parallel ntsuas lawv cov clutch sib nrig. Tsis tas li, cov txiaj ntsig ntawm kev sim tau muab piv nrog cov txiaj ntsig ntawm cov kev ntsuas no tsim tawm rau lwm txoj hlab ntshav ntawm cov yam ntxwv ntawm Askiv. Raws li nws tau muab tawm, ib qho kev hloov me me hloov hauv RBD cov qauv protein, uas yog qhov ua tau zoo tshaj lub peev xwm ntawm cov kab sib txuas lus nrog cov receptors2. Nws tau sau tseg tias nyob rau nruab nrab, qhov ntsuas no yog kaum npaug ntawm cov hom tshiab thiab nws tus neeg ua ntej ntawm cov hom tshiab thiab nws tus kheej, uas yog qhov zoo siab atypical pa.
Tawm tswv yim txog cov txiaj ntsig ntawm kev suav, cov kws kho mob tau hais tias qhov kev hloov pauv ntawm RBD protein yog vim muaj peev xwm hloov kho hydrogen thaum nws sib txuas nrog Ace2. Tsis tas li ntawd, microbiologist tau pom ntau yam kev hloov pauv ntawm cov kev sib txuas sib txuas ntawm cov molecules, tab sis lub luag haujlwm ntawm cov metamorphois yuav tsum tau ntsuas. Tab sis twb tau, cov kws tshawb fawb tau sau tseg tias cov kev hloov pauv tau muaj peev xwm txo tau cov kev ua tau zoo rau cov tshuaj tiv thaiv monoclonal ntawm cov microelements ntawm cov kab mob ntawm British. Txawm li cas los xij, raws li cov kws tshaj lij, muaj peev xwm tawm tsam tus kab mob ntawm cov kabmob COVID-19 cuam tshuam los ntawm cov kab mob yog cuam tshuam, txawm tias tsis muaj ntau li nrog cov qauv dhau los ntawm SARS-CE-2.
"British Coronavirus cov kab sib chaws N501y, hloov cov qauv ntawm kev hloov pauv ntawm cov kab mob ntawm cov kab mob ntawm tes. Peb pom tias qhov kev hloov pauv me me no tau ntev li kaum npaug ntawm tus kab mob rau Sib txuas lus nrog cov protein ntau ntawm tib neeg lub hlwb, "Cov Ntawv Sau Cov Sau Ntawv ntawm Kev Ua Haujlwm Kev Kawm, Professor Philip Marrah. Kev tshawb fawb tau muab lo rau Biorgia cov khoom siv hauv Biorxiv.