A cikin duniyar cututtukan cututtukan cututtuka, ƙwayoyin cuta masu yawa ko cututtukan fungal zasu iya rayuwa da kansu ba tare da kananan ƙware ba. Amma ƙwayoyin cuta ba za su iya ba. Madadin haka, dole ne su shiga cikin sel don ninka, inda suke amfani da kansu hanyar ɓoyayyen kayan ƙamus don ƙirƙirar sabbin ƙwayoyin cuta da kuma mutane. Kamar rayuwar tantanin halitta, coronavirese kansu suna kewaye da harsashi mai mai. Don shiga cikin sel, suna amfani da sunadarai (ko glycoproteins, kamar yadda ake sau da yawa ana rufe su da kwayoyin sukari tare da membrane sukari tare da membrane na selpery tare da sel sel selpery kuma don haka kama sel. Daya daga cikin wadannan ko bidiyo na glycoproproins shine furotin karfafawa na coronaviruse. Ganin fitowar sabbin juzu'in Coronavirus SARS-2-2, fifikon jama'a zuwa karye subbel ya karu sosai. Ya juya cewa sabon zabin Coviid-19 yana ɗaukar takamaiman canje-canje a cikin furotin mai karfafawa idan aka kwatanta da sauran zaɓuɓɓuka na kusa.
Spikes sunadarai
Ofaya daga cikin mahimman halayen halayen Coronavirus SARS-COV-2, da kuma wasu ƙwayoyin cuta waɗanda ke ba da waɗannan ƙwayoyin Spiker da ke ba da waɗannan ƙwayoyin Spiker waɗanda ke ba da waɗannan ƙwayoyin Spiker waɗanda ke ba da waɗannan ƙwayoyin Spiker waɗanda ke ba da waɗannan ƙwayoyin Spiker waɗanda ke ba da waɗannan ƙwayoyin Spiker waɗanda ke ba da waɗannan ƙwayoyin cuta don shiga cikin sel mai tallafawa kuma suna haifar da kamuwa da cuta. A matsayinka na mai mulkin, da kwayar cutar coronaviruse ta ƙunshi sunadarai uku waɗanda suka haɗa da furotin membrane (m), furotin harsashi (e) da furotin mai karu.
Jin furotin mai son kai ya ƙunshi amino acid 1160-14-1400, gwargwadon nau'in kwayar cuta. Idan aka kwatanta da m da e na sunadarai, waɗanda suke yawanci a cikin taron cutar ta, s furotin yana taka muhimmiyar rawa wajen shiga cikin sel da kuma qarancin kamuwa da cuta. Abin lura ne cewa shi ne gaban s-sunadarai a kan coronavirus yana haifar da bayyanar prayrusions na masu siffa a farfajiya.
Masu sana'a sun lura cewa sunadarai coronvirus sunadarai zuwa manyan sunadarai masu aiki na aiki, wanda ya haɗa da yankin S2 na S2, wanda aka gina kai tsaye a cikin kwasfa ta hoto. Lokacin da yake hulɗa da yiwuwar mai masaukin sel, S1 Subunit ya gane da kuma ɗaukakawa ga masu ba da izini, alhakin sashen ra'ayin mazanaci, wanda ke da alhakin haɓakar ƙwayoyin cuta tare da membrane harsashi tare da membrane harsashi .
Yana da ban sha'awa: An san an tantance kwayar cutar Rasha da aminci da aminci
Abin lura da cewa ba tare da ƙwayoyin cuta kamar SARS-Cov-2 ba, ba zai taba yin ma'amala da sel masu iyo ba, kamar dabbobi da mutane. A saboda wannan dalili ne cewa furotin s ne mai kyau manufa don binciken allurar rigakafi da kwayoyi masu amfani da su. Baya ga rawar da ta a cikin tantanin halitta, masanin kwayar cutar s-19, shine babban abin halartar kayan aiki (Nabs). Nabs shine maganin kariya wanda aka samar da shi ta hanyar tsarin rigakafi.
Spikels da rigakafin
Kwayoyinmu sun samo asali don nuna mamayar ƙwayoyin cuta. Ofaya daga cikin manyan sojojin kariya daga sel daga cikin masu ba da harsashi na waje, wanda ya kunshi mai mai da ke ɗauke da dukkan enzymes, sunadarai da DNas sun tsallake sel. Saboda yanayin ɓoyayyen halittu na mai, wanda ya mamaye cutar sosai ya shafe wannan katse don samun damar yin amfani da tantanin halitta.
La'akari da yadda mahimmancin furotin mai karfafawa shine, sakamakon yawancin alurar rigakafin rigakafi ko kwayoyi ana nufin su a hoto ko bidiyo. Aikin rigakafi da SARs-Cov-2, wanda Pfiiz da Moderna, ya ba da umarni ga tsarin garkuwarmu don yin nasu siga na karye, wanda ke faruwa bada jimawa ba bayan rigakafin. Samun samar da mai kara furotin a cikin sel ɗin mu sannan ka ƙaddamar da sel na kariya da t sel.
Cutar tana haifar da furotin mai kara guda biyu, kwayar cutar mura zaki biyu ne, kuma kwayar cuta mai sauki ce - Biyar.
Kamar yadda tattaunawar ta rubuta, daya daga cikin manyan sifofi na SARS-2-2 Spiker furotin shi ne yadda take motsawa ko canje-canje a kan lokaci a lokacin juyin halittar. Coded ɗin sunadarai a cikin gidan yanar gizo na iya maye gurbin kuma canza kaddarorin biochemical kamar yadda kwayar cutar ta taso.
Yawancin maye gurbi ba sa amfana kuma ko dai su daina aikin furotin, ko kuma ba sa shafar aikinsa. Amma wasu daga cikinsu na iya haifar da canje-canje da ke ba da sabon sigar kwayar cutar, sanya shi ƙarin watsa. Ofaya daga cikin hanyoyin da wannan zai iya faruwa maye gurbi ne a wani ɓangare na karbi da keɓaɓɓe wanda ke hana ƙwararren magunguna tare da shi. Wata hanya ita ce sanya spikes "more m" don sel.
Kana son koyaushe ka san sabon labarin daga duniyar shahararren kimiyya da fasaha na ɗaukaka? Biyan kuɗi zuwa Telegram ayoyin Telegram. A nan zaku sami sanarwar sabbin labarai na shafin yanar gizon mu!
Wannan shine dalilin da ya sa sabbin maye gurbi wanda ke canza ayyukan karye ko furotin s suna musamman da damuwa - suna iya shafar yadda muke sarrafa rarraba SARS-Cov-2. Sabbin zaɓuɓɓuka kwanan nan sun gano a Burtaniya da Afirka ta Kudu suna da maye gurbi a sassan furotin, wanda ya shiga cikin shiga cikin sel. Motar bincike da gwaje-gwajen motsa jiki zasu taimaka wa masana kimiyya gano idan - da kuma ta yaya - waɗannan maye gurbi canza yawa ta hanyar furotin mai karfin ra'ayi, da kuma matakan kiyaye su na yanzu sun kasance mai tasiri.