Masana kimiyya sun gaya wa matar Rasha da ke da Koronvirus sun sami sabbin abubuwan maye

Masana kimiyya sun gaya wa matar Rasha da ke da Koronvirus sun sami sabbin abubuwan maye

Masana kimiyya daga Cibiyar Kimiyya ta Skolkkovsk, Cibiyar ta tabbatar da matsalolin bayanan ilimin kimiyyar Rasha da kuma Cibiyar Kifin Kiwon Kididdiga ta farko da aka buga a kan Portal Portal , a cikin abin da suka gaya game da shekaru 47 da haihuwa tare da covid goma sha tara. Gaskiyar ita ce a cikin shari'arta, coronavirus ta sami mutun abubuwa 18, kuma ba ta da lafiya fiye da watanni huɗu.

A karshen watan Maris a bara, wata mata da ke da wani matakin sel nehodgkinky mataki na shirin Cheemoximab (Antitorewa wakili daga rukuni na magunguna na monatoxonal). Ta sa a cikin dakin guda tare da tsofaffi, wanda ba da daɗewa ba aka saukar da covid-19.

A ranar 17 ga Afrilu, an fitar da mace mai shekaru 47 daga asibiti, amma kasa da makonni biyu da ta kamu da cutar coronvirus. "A wannan lokacin, ya bayyana alamun covid-19 (yadda zafin jiki na jiki). An watsar da wannan asalin tushen nan da nan bayan gwaji kuma ba a samu don Sequincing ba. Maimaita bugun jini wanda aka maimaita Mayu 14, 19 ga Yuni, 9 ga Yuni da 14 ga Yuli, sun ba da mummunan sakamako a kan SSS-Cov-2. Koyaya, haƙuri a ranar 25 ga Mayu zuwa Agusta 21, alamun bayyanar cutar CoVID-19 an lura. Sakamakon gwajinta ya sake zama 3, 5, 8, 13, 17, 21, 27, kamar yadda ranar 3 ga Satumba 3 da 9. A ƙarshe, sakamakon ya kasance mara kyau a ranar 12 ga Satumba, sannan kuma sake komawa Nuwamba 10 da Disamba 16, "marubutan binciken sun rubuta.

Matsayin samfurin ƙwayar coronavirus 47 mai haƙuri a cikin layin B.1.1. Itace na phylogenetic B.1.1, an sake gina shi don jerin 49,083, an yanke shi don kunshe da sa bazuwar 1% na duk samfuran s (ja dot). Mai haƙuri a wani baƙar fata ne. Layin mai haƙuri s (ja) yana da maye gurbi 18, gami da Δ69-70hv da y435f s-furotin alamar launin rawaya da shuɗi, bi da bi. Layi B.1.1.7 da kuma Cluster 5 shaded / © basykin g.a. wani dabam

Masana kimiyya suna lura da ainihin samfurin samfurin da aka samu a ranar 20 ga Nasopharynx. Don kwatantawa, sun sanya samfurin smear (mai haƙuri a), daga wane mai haƙuri mai shekaru 47 (s) mai kamuwa da cuta ne mai kamuwa da cuta. A sakamakon haka, ya juya cewa daga tunani, Wuhan ten Srs-Cov-2, wani samfurin Russia ya bambanta canje-canje 25. "Daga cikin wadannan, bambancin guda bakwai na polymorphisms guda bakwai, gami da uku a cikin makwabta makwabta 21881-21883, an sanya su cikin samfurin mai haƙuri a layi.. Da yawa suna ɗaukar ragowar magungunan kwayoyin halitta 18. A samfurin da farko tsofaffin mai haƙuri kuma an sanya shi a cikin layin tushe B.1.1, wanda ya tabbatar da cewa maye gurbi 18 takamaiman ne ga mai haƙuri s, "in ji masana.

Don haka, marubutan rahoton, da coronavirus na ainihi daga haƙuri tare da lymphoma, sabbin maye gurbi ne daga 24 ga Afrilu-3 canje-canje zuwa Mutun nucleotide a shekara, wannan shine, yana da muhimmanci ya wuce matsakaicin juyin halitta ya rage mahimmancin SARS-CoV-2. Ciki har da maye gurbi na s-furotin y453f da Δ69-70hv ("hade ΔF", wanda aka saukar ne a gurbataccen mink coringavirus.

"An samo maye gurbi a cikin haƙuri tare da mita matsakaici: Wannan lamari ne na Polymorphism a cikin mai masa masa masa mai masaukin. Tun lokacin bincike na phylogenetic ya nuna cewa an sake yin shinge da Mink ɗin, maye gurbi. A hannun mai zaman kanta da canje-canje na canje-canje a cikin mink da haƙuri tare da Lymphoma, da kuma tsakanin yawancin marasa lafiya, ya shafi canje-canje da aka amince da su a cikin zaɓi. Mai haƙuri S ya ba da samfurin kawai don yau tare da haɗuwa da Y453F da s wins: Δ69HV a bayan gungu 5, "sun kara da kansu da kansu.

Spikelists a cikin sanannun coronavirus bambance-bambancen coronavirus da kuma yin rijista na abin da ake kira tsawan lokaci-19. Nuna maye gurbi na amino acid a ɓoye ta mai karu. Layuka daga sama zuwa kasan: 501y: bambance-bambancen V2; version voc-202012/01 (zuriyar Ingila); zaɓi zaɓi 5; Haƙuri tare da rigakafi mai rauni, karbar wani plasma; Mai haƙuri tare da rigakafi mai rauni, karɓar cakuda abubuwan ƙwayoyin moniclonal Regeneron; Mai haƙuri tare da rigakafi mai rauni, suna karɓar plasma na murmurewa; Mai haƙuri tare da rigakafi mai rauni wanda bai karɓi magani tare da plasma ko gogewar murmurewa ba. An lura da launuka masu haske da aka lura da maye gurbi a cikin karatun guda biyu / © basykin g.A. wani dabam

Bugu da kari, mai haƙuri ya bayyana ƙarin maye gurbi guda biyu, wanda a baya ya samu a wasu marasa lafiya da COVID-19 tare da raunin kai, gami da N501Y. Wannan canji yana nan a cikin abin da ake kira Inji na Burtaniya na Coronavirus da sigar Afirka ta Kudu.

"Tunda ana siyar da waɗannan maye gurbi tare da haɗuwa (wato, kama da genotype, wanda ya zama ruwan dare ga marasa lafiya da kuma, zai yiwu don mink, amma ya bambanta daga wannan a cikin yawan jama'a. Koyaya, zaɓuɓɓuka da aka gano a cikin marasa lafiya da ke raunana rigakafi (da suka shafi halayen kewaya juzu'i, "marubutan binciken da aka taƙaita.

Shugaban kungiyar kimiyya Gregory Basynkin, Farfesa daga Cibiyar Kimiyya ta Skolkovsky ta Skolkovsky ta Skolkovsky, wacce aka lura a cikin sharhin na kafofin watsa labarai na Rasha, kamar yadda aka bayyana a cikin shari'ar - guda daya. "Don yanayin sararin samaniya na gaba ɗaya, baya wakiltar mahimmancin mahimmanci. Ana fatan wannan ƙwayar cuta, wacce ƙwayar cuta, wacce ta samo asali a jikin wannan haƙuri, ba ta tafi ko'ina ba. Maimakon haka, waɗannan suna ƙoƙarin fahimtar yadda wannan ƙwayar cuta ta ta samo asali kuma menene zaɓin yanayi yake aiki akan sa, "ya jaddada.

Source: Kimiyya mara kyau